Effects of Estradiol and Methoxychlor on Leydig Cell Regeneration in the Adult Rat Testis
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چکیده
منابع مشابه
Effects of Estradiol and Methoxychlor on Leydig Cell Regeneration in the Adult Rat Testis
The objective of the present study is to determine whether methoxychlor (MXC) exposure in adulthood affects rat Leydig cell regeneration and to compare its effects with estradiol (E2). Adult 90-day-old male Sprague-Dawley rats received ethane dimethane sulfonate (EDS) to eliminate the adult Leydig cell population. Subsequently, rats were randomly assigned to four groups and gavaged with corn oi...
متن کاملA Short-Term Exposure to Tributyltin Blocks Leydig Cell Regeneration in the Adult Rat Testis
Background: Tributyltin (TBT) is widely used as an antifouling agent that may cause reproductive toxicity. The mechanism of TBT on Leydig cell development is still unknown. The objective of the present study was to investigate whether a brief exposure to low doses of TBT permanently affects Leydig cell development and to clarify the underlying mechanism. Methods: Adult male Sprague Dawley rats ...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2014
ISSN: 1422-0067
DOI: 10.3390/ijms15057812